In our subject, instead, there is evidence of hypercalciuria, in line with Carling et al. study [19], that identified a family with a heterozygous inactivating mutation of the cytoplasmic domain of the CaSR, not far from that of the patients in our study, associated with hypercalcemia, hypercalciuria and unsuppressed PTH. Here, CASR is linked to Hypercalcemia.