The principal findings of this study were as follows: 1) the NLR had a better overall diagnostic performance than maternal serum CRP levels in predicting PIR and distinguishing HCA from funisitis; 2) patients with a high NLR were at risk of impending preterm delivery in the context of normal CRP levels; and 3) the combined use of NLR and CRP levels measured before treatments can predict poor pregnancy outcomes in patients with PIR. Here, CRP is linked to hepatocellular adenoma.