KLRK1 and neoplasm: This induction also provided an explanation for the observed enhanced tumor initiation by untransfected MCF-7 cells expressing minimal endogenous NKG2D (Figure 1G; for flow cytometry profiles of the parental MCF-7, MCF-7–NKG2DRNAi, and MCF-7–scrRNAi lines see Figure S1A and S1G) [9].