TLR4 and duodenal ulcer: Garza-Gonzalez et al reported that there was no correlation between TLR4 polymorphisms and gastric cancer in Mexican ethnicity [27], however, Trejo-de la et al insisted that both SNPs (+896A/G and +1196C/T) within TLR4 had an increased susceptibility to gastro-duodenal diseases including duodenal ulcer and gastric cancer [24].