Consistent with the conclusions resulted from the mentioned studies, our results demonstrate that both +896A/G and +1196C/T TLR4 polymorphisms are associated with a significantly increased gastric cancer, especially for genotype model (heterozygous: AG vs. AA, dominant: GG+AG vs. AA, heterozygous: CT vs. CC, dominant: CT+TT vs. CC) and additive model (G vs. A and T vs. C). Here, TLR4 is linked to gastric cancer.