WFS1 and Low-frequency sensorineural hearing impairment: WFS1 has also been linked to an autosomal dominant form of low-frequency sensorineural hearing loss (LFSNHL) [24]–[26], autosomal dominant optic atrophy (ADOA) [26]–[28], type 2 diabetes [29]–[31] and psychiatric problems [27], [32], [33].