FUS and amyotrophic lateral sclerosis: Several reports have recently emerged demonstrating the effect of arginine methylation on the cellular localization of endogenous and ALS-linked FUS proteins, with a consistent finding that nuclear export of FUS requires arginine methylation (Dormann et al., 2012; Du et al., 2011; Sama et al., 2013; Tradewell et al., 2012; Yamaguchi & Kitajo, 2012).