Genes encoding IL1R1 (1.99, p<0.04), OPRM1 (2.65, p<0.02), SIGMARI (3.13, p<0.03), THRB (1.94, p<0.02) and ZFP91 (3.09, p<0.01) mRNA were upregulated in the gastric tissue of patients with non-alcoholic steatohepatitis (NASH) compared to those without NASH. Here, OPRM1 is linked to metabolic dysfunction-associated steatohepatitis.