Other signaling pathways have not been identified in DLBCL, however, may influence numerous processes in other types of cancer; for example, hsa-miR-15a/hsa-miR-16-1 targets BCL2 and exerts an etiological and therapeutic role in keratocystic odontogenic tumors (26), and hsa-miR-16-1 targets CCND1 in mantle cell lymphoma (27). This evidence concerns the gene BCL2 and cancer.