Another group is associated with defect of nuclear envelope proteins, encoded by LMNA, ZMPSTE24 and BANF1 et al., such as HGPS and MADA mutated in LMNA, MADB mutated in ZMPSTE24, and Nestor–Guillermo progeria syndrome (NGPS) in BANF1[4, 9, 10]. This evidence concerns the gene LMNA and Nestor-Guillermo progeria syndrome.