A statistical analysis revealed that the positive expression rate of GOLPH3 in the gastric cancer group strongly correlated with histological grade (p = 0.011), depth of invasion (p = 0.007), distant metastasis (p = 0.002), and lymph node involvement (p<0.004), whereas it did not significantly correlate with age or gender (p = 0.801 and 0.833, respectively). This evidence concerns the gene GOLPH3 and gastric cancer.