BCL2 and cancer: Anti-apoptotic B cell-chronic lymphocytic leukemia/lymphoma 2 (Bcl-2) family members (Bcl-2, Bcl-XL, Bcl-w, Bcl-b, A1/Bfl-1, and Mcl-1) are overexpressed in many cancers and inhibit apoptosis by sequestering pro-apoptotic members of the family (BH3-only proteins, and Bax and Bak) [4], [5].