HDAC3 and neoplasm: The maturation of INPs requires Numb, the NHL family protein Brain tumor (Brat), the transcription factor Earmuff (Erm), as well as the BAP and Histone deacetylase 3 (HDAC3) chromatin remodeling complexes (Bowman et al., 2008; Weng et al., 2010; Eroglu et al., 2014; Koe et al., 2014).