The first two statements born from data shown in Figures 6 and7 in which we observed that Selinexor, a clinically relevant potent and oral available XPO1 inhibitor, was able to increase apoptosis (anoikis) when PC-b2 and DU145 tumor cells were seeded in tissue culture dishes coated with poly HEMA and thus forced to grow in suspension. The gene discussed is XPO1; the disease is neoplasm.