To determine the effects of ABRO1 on tumour cell growth, an ABRO1 expression vector was transfected into cells of the human HCC cell line HepG2, the human breast cancer cell lines MCF-7 and BT474, the human neuroblastoma cell line SKNSH, the human non-small cell lung cancer cell line A549, the human lung cancer cell line H1299 and the human colon cancer cell line HT-29, and G418-resistant clones were established. The gene discussed is ABRAXAS2; the disease is malignant colon neoplasm.