Clinical topics also influenced perceptions of the relevance of the information provided in the Dbox (with maximal values obtained by the Prenatal Dbox and minimal values by the BRCA1/2 gene mutation test to evaluate the risks of breast and ovarian cancer (BRCA) Dbox) and perceptions of problems with the information, with more problems perceived with regard to the acetylsalicylic acid for primary prevention of cardiovascular disease (ASA) Dbox and fewer problems with the Prenatal Dbox. Here, BRCA1 is linked to cardiovascular disorder.