These phenomena might, at least in part, be due to the dual role of TRPS1 as both an oncogene and a tumor suppressor during breast cancer development: The tumor suppressor role of TRPS1 might be due, to some extent, to its function as a negative regulator of EMT and the higher expression of TRPS1 could reduce the tumor's potential for metastasis. Here, TRPS1 is linked to breast carcinoma.