NFKB1 and ovarian carcinoma: Indeed, our results using Western blotting and NF-κB promoter luciferase assays clearly show that TAK1 is able to modulate NF-κB signaling activity, whereas either co-treatment with TAK1 inhibitor, (5Z) -7-Oxozeaenol, or shRNA-mediated TAK1 knockdown abrogates TAK1's effect on NF-κB signaling activity in ovarian cancer cells.