After normalizing gene dosage data and comparing them to HK-2 cells, we observed a reduction of the 5′ region of TRIM8 gene (region 1) equal to about 0.5 in RCC Shaw cells and 0.2 in RCC Elthem cells, and similar ratios were calculated for the 3′ region (region 2), i.e., about 0.4 and 0.1, respectively in RCC Shaw and Elthem cell lines (Figure 3C). This evidence concerns the gene TRIM8 and renal cell carcinoma.