We also demonstrated that the methylated statuses of four CpG sites (CpG -236, CpG -183, CpG -162, and CpG -152) of PAX5 promoter had significant association with the survival of 460 GC patients (P =0.025, =0.019, =0.010, and =0.020), respectively. Here, PAX5 is linked to gastric cancer.