PEBP1 and nonpapillary renal cell carcinoma: Within the 15 cases of local carcinoma with metastasis, tissues from the metastasized organ (adrenal gland, bone, lymph node, lung, thyroid, intestine, and spleen) were available for 8 cases; the RKIP levels were significantly lower in metastasized ccRCC compared to the local counterparts (Fig. 3F, G).