Therefore, cancer patients were further stratified into four subgroups by using the median of SNA binding and anti-TF IgM level values for the combined group of cancer patients as follows: (1) patients with an SNA binding value that is equal to or more than median and anti-TF IgM level that is equal to or more than median; that is, SNA ≥ IgM ≥, (2) SNA < IgM ≥, (3) SNA ≥ IgM <, and (4) SNA < IgM < subgroup (see the table in Figure 5). The gene discussed is TF; the disease is cancer.