IL10 and Stroke: On the other hand, recovery from stroke has also been associated with upregulation of the anti-inflammatory cytokines, IL-10 and TGF-β1 [66, 67], and treatment with LXA4 or BML-111 (the stable synthetic LXA4 analogue 5(S),6(R)-LXA4 methyl ester) has been reported to increase the levels of such cytokines in stroke models involving both the peripheral and the central nervous systems [38, 68].