WNK1 and hereditary sensory and autonomic neuropathy: Mutations in the WNK1 gene have been shown to be causative of the hereditary sensory neuropathy in a French family with PHA2 and defects in peripheral sensory perception; the authors demonstrated that WNK1 is highly expressed in the sensory components of peripheral nervous system and is associated with relaying sensory and nociceptive signals in sensory neurons [86, 88].