CXCL10 and infection: In vitro infection of cultured adipocytes with T. cruzi revealed that a panel of proinflammatory cytokines was upregulated; these include IL-1β, IFN-γ, TNF-α, chemokine ligand (CCL2), CCL5, and C-X-C motif chemokine 10 (CXCL10) The expressions of TLR-2 and 9 are also upregulated [8].