Interestingly, several cancer-related genes (VHL, HIF1A, cMET, phosphatase and tensin homolog, TSC1, BCL2, BRCA1), which include some tumor suppressors, were also found to be overexpressed in both the benign oncocytoma-like region and the high-grade oncocytic carcinoma region. Here, TSC1 is linked to oncocytic adenoma.