To summarize, Ang-2 and Ang-2/Ang-1 have been considered as predictive biomarkers for the severity of various pathologies, both non-infectious [45], [46], [47] and infectious [32], [48], including falciparum malaria [15], [23], [49], [50]. This evidence concerns the gene ANGPT2 and Plasmodium falciparum malaria.