Amongst bleeding disorders, hemophilia A (FVIII deficiency), hemophilia B (FIX deficiency) and von Will brand disease (vWD) are most commonly occurring, whereas deficiencies of fibrinogen, prothrombin (FII), factor V (FV), combined factor V and VIII (FV+VIII), factor VII (FVII), factor X (FX), factor XI (FXI) and factor XIII (FXIII), along with platelet disorders, Glanzmanns Thrombasthenia (GT) and Bernard Soulier Syndrome (BSS) are rare worldwide, including India. This evidence concerns the gene F5 and Bernard-Soulier syndrome.