Nguyen et al. reported that SBP increased significantly in mice that received IL-17A (IP injection of 1 μg/d for 7 d), which was attributed to a decrease in the response to aortic nitric oxide (NO)-dependent relaxation and an increase in NO synthase Thr495 phosphorylation (which leads to a decrease in NO production and vasodilation, and is associated with HT) [5]. This evidence concerns the gene IL17A and hematocrit.