STAT1 and inflammatory bowel disease: The observed reduction of activated STAT1 accumulated in the nucleus induced by Resv in HT-29 cells, may have an extremely important impact in the context of IBD, since besides its implications for the inhibition of many pro-inflammatory genes, it can contribute for the prevention of radiation resistance acquired by IBD patients during radiotherapy treatment, which has been associated to high levels of nuclear STAT1 [42].