Higher expressions of CXCR1, CXCR2, and CXCR4 with their ligands CXCL5, CXCL8, and CXCL12 appear to be associated with tumor angiogenesis, metastasis, and poor survival in NSCLCs (5,22–26). The gene discussed is CXCL8; the disease is neoplasm.