PTGS2 and neoplasm: In all the statistically significant cases the enhanced COX-2 expression in tumour epithelial cells had negative influence on the outcome with relatively high hazard ratios (HR) for overall survival (ALG 1: HR(Ab2) = 10.01 [95% CI 2.69 – 37.29], HR(Ab3) = 4.75 [95% CI 1.26 – 17.79]; ALG 2: HR(Ab2) = 3.56 [95% CI 0.8 – 15.78], HR(Ab3) = 2.71 [95% CI 0.57 – 12.52]; ALG 3: HR(Ab2) = 10.01 [95% CI 2.69 – 37.29].