TNFAIP3 and multiple sclerosis: Some of the differentially regulated genes, such as the IL-7 receptor (Ilr7) (Gregory et al, 2007), tumor necrosis factor receptor superfamily 12, TNFRSF12/DR3 (Pappu et al, 2008) and TNF alpha induced protein 3 (TNFAIP3) (Prahalad et al, 2009) are known to confer susceptibility to multiple sclerosis.