FGF14 and Ataxia: An ataxia phenotype in Fgf14−/− mice highlights the role of FGF14 in cerebellar physiology and the development of spinocerebellar ataxia type 27 (SCA27) in patients with either FGF14 haploinsufficiency or a dominant negative FGF14 mutation (Wang et al., 2002; van Swieten et al., 2003; Dalski et al., 2005) underscores the role of FGF14 in disease.