Univariate analysis identified the following prognostic risk factors in the total population: tumor number ≥3, serum AFP ≥400 ng/mL, serum albumin <4 g/dL, serum alanine aminotransferase >80 U/L, serum bilirubin >1.2 mg/dL, macrovascular invasion, major hepatectomy, and PHT. The gene discussed is AFP; the disease is neoplasm.