SLC31A1 and small cell lung carcinoma: For example, enhanced expression of the human Ctr1 gene in cancer cells normally resistant to cisplatin (including small cell lung cancers SCLC, and SR2 cells) led to an accumulation of cisplatin, carboplatin, and oxaliplatin, suggesting that hCtr1 can transport not only cisplatin but also carboplatin and oxaliplatin, albeit at reduced rates [27].