(Figure S1) The comparison between CRC patients and healthy donors (HD) revealed that LAP expression in CD4+Foxp3+ T cells isolated from PBMCs was significantly increased in cancer patients (CRC: 18.8%±9.2% vs. HD: 7.8%±3.3%; Fig. 1A and B). Here, TGFB1 is linked to colorectal carcinoma.