ANK1 and malaria: A dominant ENU-mutagenesis screen for erythrocyte production and maturation defects linked to malaria resistance identified two mutations in the Ank1 gene: an alternative splice acceptor mutation resulting in a frameshift mutation and premature stop codon was identified in Mpl−/− mice mutagenized on a BALB/c background [127], and a single nonsense mutation was identified in mutagenized SJL/J mice [128].