Sixty-seven cases of ABCG2 expression in diffuse large B-cell lymphoma (DLBCL) using immunohistochemistry are reported and it was found that ABCG2 expression levels were positively correlated with sonic hedgehog ligand expression and that patients with high ABCG2 expression showed significantly shorter overall survival (p = 0.031) and failure-free survival (p = 0.029) compared with patients with low or no expression of ABCG2 [105]. The gene discussed is ABCG2; the disease is diffuse large B-cell lymphoma.