Further, we extracted the data from The Cancer Genome Atlas (TCGA, https://tcga-data.nci.nih.gov/tcga/) and they also confirmed a link between hypomethylation of MN1 and DHRS3 regulatory regions and their overexpression in inv(16) AML when compared with AML samples with normal karyotype (healthy controls data were not available). This evidence concerns the gene DHRS3 and acute myeloid leukemia.