DNAH8 and systemic lupus erythematosus: It has recently been shown that the specific reorganization of the immune system during spontaneous development of a profound SLE-like pathology in MRL-lpr/lpr mice is associated with changes in the differentiation profile and the level of proliferation of bone marrow hematopoietic stem cells and with the production of DNase, ATPase, and amylase abzymes [39]–[41].