CST3 and Hypertension: For the prediction of CVD hospitalization and/or mortality, the AUCs varied between 0.660 (95%CI 0.622, 0.712), 0.659 (95%CI 0.621, 0.710; Sidak p-value 0.974) and 0.660 (95%CI 0.622, 0.712; Sidak p-value 0.996) respectively using the CKD-EPI creatinine, CKD-EPI cystatin C and CKD-EPI creatinine-cystatin C equations adjusted for age, BMI, hypertension, diabetes, systolic blood pressure, prevalent renal disease and CVD, smoking history and treatment group (Figure 3).