Intraductal papillary mucinous neoplasms (IPMN) have been increasingly recognized as an intraductal mucin-producing pancreatic neoplasms with tall, columnar mucin-containing epithelium and a lack of ovarian stroma, according to the World Health Organization definition [1], [2]. The gene discussed is MUC5AC; the disease is pancreatic intraductal papillary-mucinous neoplasm.