For this, we compared the extent of metastasis resulting from the intracardiac injection of both naïve Hec1A cells (Figure 4B, upper panels), and ETV5 over-expressing Hec1A cells (Figure 4B, lower panels), further modified to constitutively express the luciferase reporter gene and allow vital bioluminescent imaging of disseminating tumor cells. This evidence concerns the gene ETV5 and neoplasm.