CD4 and Duchenne muscular dystrophy: In individuals with DMD, it has been shown that a larger number of CD4+ and CD8+ CD49dhi circulating cells are present in severely affected individuals; in comparison to the same subset of cells in healthy individuals, these cells in DMD individuals have an enhanced migration capacity, and are also a component of the lymphocytic population present in the muscles, where they probably contribute to the deleterious inflammatory process (F.P.-M., W.S., S.D.S.-B., V.M., T.V., G.B.-B.