The non-overlapping expression of ER and PR in normal breast was validated in independent cohorts (normal breast n=50; breast cancer n=66), where we had previously measured the transcript expression of ER, PR and the other members of the nuclear receptor (NR; n=48) gene family, and all known NR co-regulators (CoRs; n=238) [35]. Here, C1QTNF3 is linked to breast cancer.