TGF-β1 is known to play pivotal roles in promoting tumor cell invasion and metastasis and is overexpressed in advanced cancers including HCC.[26-28] We therefore examined whether Dp44mT could act against the TGF-β1- induced EMT in MHCC-97L and SMMC-7721 cells. Here, TGFB1 is linked to hepatocellular carcinoma.