Overall survival was significantly correlated with galectin-3 expression (P < 0.01), CD34 (P = 0.049), tumor size (P = 0.005), and histological differentiation (P = 0.032), but not with sex, age, cirrhosis of the liver, serum level of alpha fetoprotein (AFP), serum level of the surface antigen of the hepatitis B virus (HBSAg), metastasis, or recurrence (Table 2). Here, AFP is linked to neoplasm.