PLOD1 and hypogonadotropic hypogonadism: Hormonal assessment was performed two months later, after the stabilization of the cardiac condition, confirming severe hypogonadotropic hypogonadism [testosterone <0.02 ng/mL; follicle-stimulating hormone (FSH) 0.18 mU/mL; luteinizing hormone (LH) <0.1 mU/mL].