Platelets secrete cytokines and growth factors such as TGF-β [16], VEGF [17], MMP-2, PF4 [18] and PDGF [19], which in turn induce hallmarks of cancer progression such as epithelial-mesenchymal transition (EMT) [20], angiogenesis, cell migration and/or proliferation. This evidence concerns the gene TGFB1 and cancer.