Our analysis of myosin IC isoform expression in these tissues revealed a markedly increased presence of myosin IC isoform A in cells associated with characteristic PIN lesions of TRAMP mice when compared to cells of wild type prostate tissue in which myosin IC isoform A is barely detectable (Figure 3C&D). The gene discussed is MYO1C; the disease is prostate intraepithelial neoplasia.